Prevalence of Estrogen Receptor b mRNA in Human Vascular Smooth Muscle and Transcriptional Effects
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چکیده
Yvonne K. Hodges, Lin Tung, Xiang-Dong Yan, J. Dinny Graham, Kathryn B. Horwitz and Vascular Smooth Muscle and Transcriptional Effects mRNA in Human β : Prevalence of Estrogen Receptor β and α Estrogen Receptors Print ISSN: 0009-7322. Online ISSN: 1524-4539 Copyright © 2000 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Circulation doi: 10.1161/01.CIR.101.15.1792 2000;101:1792-1798 Circulation. http://circ.ahajournals.org/content/101/15/1792 World Wide Web at: The online version of this article, along with updated information and services, is located on the
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Increased expression of estrogen receptor-beta mRNA in male blood vessels after vascular injury.
Estrogen exerts direct effects on vascular endothelial and smooth muscle cells that are important for vascular protection. Estrogen receptor-alpha (ERalpha) is expressed in vascular cells from males and females and may mediate some of the effects of estrogen on vascular tissue. However, we recently found that estrogen is able to protect against vascular injury in ovariectomized female ERalpha k...
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